Seroquel (quetiapine) is an antipsychotic drug approved for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. However, doctors, at the aggressive urging of AstraZeneca, have also been known to prescirbe this medication for off-label uses.

It was thought that Seroquel would be useful in the treatment of delusions and aggression in Alzheimer's patients. However, the potential benefits do not outweigh the risks that have been seen in these populations. When prescribed to elderly patients in these circumstances, Seroquel has been shown to lead to major complications and even sudden death.

Three-fourths of the 4.5 million Americans with Alzheimer's disease develop aggression, hallucinations, or delusions, which can lead them to lash out at caregivers or harm themselves. This behavior is the most common reason families put people with Alzheimer's in a nursing home.

Multiple recent drugs for schizophrenia were tested for effectiveness in treating these Alzheimer's symptoms, including: Zyprexa, Risperdal and Seroquel. Doctors are free to prescribe them for any use. However, the drugs carry a strong warning that they increase the risk of death for elderly people with dementia-related psychotic symptoms, mainly because of heart problems and pneumonia , and that they are not approved for such patients.

However, at one point roughly one-quarter of nursing home patients were on these drugs, and at least that many patients at home have used them, mainly because there are no great alternatives and there was some evidence they might help.

AstraZeneca's off-label marketing of this Seroquel, particularly when it has been suggested to lead to such serious side effects, is not only unethical, but illegal.

If you or a loved one has been prescribed Seroquel and suffered serious side effects, contact us today to determine if you may have a personal injury claim.

  • Testosterone is a male sex hormone that naturally decreases in the body as a man ages. This dip in testosterone levels can cause symptoms such as such as fatigue, depression, low libido, decreased muscle mass, and increased body fat.

    In recent years, millions of American men have been prescribed testosterone replacement drugs to combat these typical signs of aging. In fact, the companies that make these “Low-T” drugs use aggressive marketing to encourage patients and doctors to continue using these products that can sometimes have dangerous side effects.

  • Thousands of American women have undergone surgery for the insertion of products known as transvaginal mesh or surgical mesh implants. This surgical procedure is done, typically in older women, to correct for the effects of pelvic organ prolapse, when the internal body structure requires additional support to prevent the sagging of organs such as the urethra, cervix, and rectum. Transvaginal mesh is intended to repair this issue and ensure fewer health problems going forward.

  • Trasylol (aprotinin) is a drug that was widely used in surgery to help reduce bleeding. This drug was injected during complex surgery, such as heart and liver surgery, with the main effect of the slowing down of fibrinolysis, the process by which blood clots break down. The goal was to reduce the need for blood transfusions and organ damage due to hypotension.

  • Viagra and the related drug Revatio (sildenafil), both formulated and sold by the drug company Pfizer, are used to treat erectile dysfunction (ED) and pulmonary hypertension. Millions of men have utilized these medications to remedy these conditions and improve their day-to-day quality of life.

  • Vioxx (rofecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) that was prescribed and marketed for osteoarthritis, acute pain, and dysmenorrhea. Throughout its time on the market, millions of people around the world were prescribed this medication.

  • Voltaren (diclofenac) is a nonsteroidal anti-inflammatory drug used for reducing inflammation and relieving pain. It is used to treat primarily acute pain, inflammatory disorders, and dysmenorrhea.

    Following the news that Vioxx carries a markedly high risk of cardiovascular incidents and heart disease, all other NSAIDs came under scrutiny as well. While Vioxx was pulled from the market, Voltaren and many other NSAIDs continue to be sold and prescribed. However, it may be that Volatern carries as high a risk of heart attack or stroke as Vioxx.

  • Xarelto is a blood-thinning drug which is used to reduce the risk of blood clots and stroke in patients with atrial fibrillation or “AFib” (irregular heartbeat) or patients who are recovering from certain surgical operations.

  • Zofran (ondansetron) and its dissolvable sister drug Zuplenz are drugs originally developed to treat nausea in cancer patients. GlaxoSmithKline, the drug company responsible for Zofran, in an effort to capitalize on another segment of the market, encouraged the prescription of this medication for nausea in pregnant women.

  • Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI) antidepressant that is widely prescribed in the United States. As of 2013, over 40 million Americans were prescribed Zoloft. It is primarily prescribed for major depressive disorder but can also be used for treating obsessive-compulsive disorder (OCD), panic disorder, and social anxiety disorder, in both adults and children.

  • Zyprexa (olanzapine) is an atypical antipsychotic approved in the United States for the treatment of bipolar disorder and schizophrenia. It is also prescribed by some doctors for off-label uses, with no documented proof of effectiveness.

    Some patients claim that Eli Lilly, the manufacturer of Zyprexa, did not properly warn patients about the potential side effects that can occur while taking this medication. It has been alleged that Zyprexa can actually cause diabetes and other illnesses. At the very least it appears that the drug can lead to non-trivial hyperglycemia in patients that already have diabetes.